High Flow Therapy vs Hypertonic Saline in Bronchiolitis

• Status: Completed
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to demonstrate that heated, humidified, high-flow nasal cannula (HHHFNC) is superior to hypertonic saline solution (HSS) in the treatment of moderate acute viral bronchiolitis in infants in improving respiratory distress and comfort and reducing length of hospital stay (LOS) and admission to Pediatric Intensive Care Unit (PICU).

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ministry of Health, Spain
• Treatments: Epinephrine; Epinephryl borate; Pharmaceutical Solutions; Racepinephrine

Criteria

Inclusion Criteria:

• Children aged 6 months or less

• Moderate (Respiratory Distress Assessment Instrument score of 4 or greater) viral bronchiolitis (as defined by McConnockie)

• Meeting Admission criteria

Exclusion Criteria:

• History of prematurity

• Chronic lung disease

• Cystic fibrosis

• Congenital heart disease

• Neuromuscular disease

• Airway anomalies

• Immunodeficiency

• Those requiring immediate intubation and ventilation.