This is a phase II randomized double-blind placebo/standard of care trial to determine if
rapidly inducing vitamin D sufficiency in patients with acute optic neuritis results in less
damage/greater recovery at 12 months as measured by optical coherence tomography, visual
evoked potentials, visual acuity and radiological measures. Our hypothesis, based on earlier
observational studies, is that acute optic neuritis in the context of vitamin D sufficiency
results in better visual outcomes compared to those that are not sufficient acutely,
regardless of such interventions as steroid therapy.
Phase:
Phase 2
Details
Lead Sponsor:
University of Calgary
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins