High Dose Vitamin C Intravenous Infusion in Patients With Resectable or Metastatic Solid Tumor Malignancies
Status:
Recruiting
Trial end date:
2023-01-01
Target enrollment:
Participant gender:
Summary
This is a multicenter, single arm, 3-cohort, open-label trial of high dose Vitamin C
intravenous infusion in subjects with solid tumor malignancies who are eligible for resection
(cohort A) or with extended RAS (e.g.KRAS or NRAS) or BRAF mutation metastatic cancer who
have received prior systemic treatment (cohort B). Cohort C will involve patients with
colorectal cancer having an extended RAS or BRAF mutation who are amenable for localregional
therapy of hepatic metastases with Yttrium-90 radioembolization.