High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour

• Status: Completed
• Trial end date: 2016-10-08
• Target enrollment: 0
• Participant gender: Female

Summary

In a randomized control trial conducted in six study centers/labour wards in Sweden, consenting nulliparous women in active phase of labour and with a defined delayed labour progress will be randomized to receive a regimen of either high or low dose of oxytocin. Primary outcome is caesarean delivery rate. Secondary outcomes are: Apgar score, need of neonatal intensive care, hyper-stimulation of contractions, spontaneous vaginal birth rate, length of labour, postpartum haemorrhage, sphincter lacerations, experienced labour pain, epidural analgesia and the women´s childbirth experience one month postpartum (assessed with Childbirth Experience Questionnaire). Study results will contribute to establish good evidence-based routines regarding oxytocin treatment of delayed labour progress.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Göteborg University
• Collaborator: Vastra Gotaland Region
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• Healthy nulliparous women

• singleton pregnancy

• normal pregnancy

• cephalic presentation

• spontaneous onset of active labour

• at term (37 - 42weeks gestation)

• delay or arrest of active labour

Exclusion Criteria:

• Non-Swedish speaking women

• previous uterine surgery

• intrauterine growth retardation > - 22%

• malpresentation at time of inclusion

• intrapartal hemorrhage at time of inclusion

• nonreassuring fetal-heart pattern at time of inclusion

• meconium at time of inclusion