Overview High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly Status: RECRUITING Trial end date: 2029-01-01 Target enrollment: Participant gender: Summary To learn if giving ruxolitinib and busulfan before a stem cell transplant can help to reduce spleen size and help the transplant to succeed.Phase: PHASE2 Details Lead Sponsor: M.D. Anderson Cancer CenterCollaborator: Incyte CorporationTreatments: BusulfanCyclophosphamideeltrombopagfludarabinefludarabine phosphateLevetiracetamMesnaromiplostimruxolitinibTacrolimus