High-Dose Methotrexate in Treating Young Patients With Solid Tumors
Status:
Completed
Trial end date:
2009-08-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as high-dose methotrexate work in different ways
to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Chemoprotective drugs, such as leucovorin calcium, may protect normal cells from
the side effects of chemotherapy.
PURPOSE: This phase I trial is studying the side effects, best way to give, and best dose of
high-dose methotrexate in treating patients with solid tumors.