High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as methotrexate, work in different ways to stop
tumor cells from dividing so they stop growing or die. Leucovorin may decrease side effects
caused by high-dose methotrexate.
PURPOSE: This phase II trial is studying how well giving high-dose methotrexate together with
leucovorin works in treating patients with newly diagnosed glioblastoma multiforme.