Gestational diabetes mellitus (GDM), defined as hyperglycemia with blood glucose values above
normal but below those diagnostic of DM, and iron deficiency (ID) with or without anemia
(IDA) are common during pregnancy. Both disease patterns are associated with an increased
risk of complications during pregnancy and at delivery and may have a variety of negative
effects on different aspects of child development. Thus, GDM and ID/IDA during pregnancy
should be prevented.
Whether iron supplementation with high oral doses acutely increases hepcidin during
pregnancy, and whether this acute iron-induced increase in hepcidin decreases insulin
sensitivity, is uncertain.
Phase:
N/A
Details
Lead Sponsor:
Swiss Federal Institute of Technology
Collaborators:
University Hospital, Zürich Women's clinc University Hospital Zurich