Hepato-renal Regulation of Water Conservation in Heart Failure Patients With SGLT-2 Inhibitor Treatment
Status:
Recruiting
Trial end date:
2021-06-30
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate the effects of Dapagliflozin (FORXIGA) 10mg
(n=20) and placebo (n=20) on the renal concentration mechanism, mobilization of Na+ from
tissue stores, and mobilization of muscle glycogen and fat, in patients heart failure NYHA
classes I and II,with or w/o T2DM in a 4-week double-blind, placebo-controlled, randomized
study with 2 treatment arms.