Hepatic Arterial Infusion With Floxuridine and Dexamethasone in Combination With Intravenous Oxaliplatin Plus Irinotecan in Patients With Unresectable Hepatic Metastases From Colorectal Cancer

• Status: Completed
• Trial end date: 2021-06-28

Summary

The purpose of this study is to see how well patients tolerate the side effects of treatment with Floxuridine, Oxaliplatin and Irinotecan. We also want to know if these methods used together are a useful way of treating cancer. We have studied these drugs and know the best doses of each when they are used alone. We do not yet know how well the drugs work with each other. This study will tell us the best doses of each drug when they are given over the same period of time.

• Phase: Phase 1

Details

• Lead Sponsor: Memorial Sloan Kettering Cancer Center
• Collaborators: Rutgers, The State University of New Jersey; Sanofi; University of Medicine and Dentistry of New Jersey
• Treatments: BB 1101; Camptothecin; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Floxuridine; Irinotecan; Oxaliplatin