Hemodynamic and Headache-Inducing Effect of Intravenous Vasoactive Intestinal Peptide in Migraineurs
Status:
Completed
Trial end date:
2005-09-01
Target enrollment:
Participant gender:
Summary
We hypothesized that infusion of VIP may induce headache/migraine in migraineurs and that
VIP-induced headache may be associated with dilation of intra- and extracranial vessels. To
test this hypothesis, we performed a double blind placebo-controlled crossover study in
migraineurs and studied the effect on headache and cerebral and systemic hemodynamic
parameters.