Hemodynamic Protection of Preoperative Ondansetron 15 Minutes Before Spinal Anaesthesia in Caesarean Section
Status:
Completed
Trial end date:
2017-01-02
Target enrollment:
Participant gender:
Summary
Spinal anaesthesia for caesarean section is the most commonly used anaesthetic choice in
caesarean deliveries. This is usually associated with maternal hypotension and other adverse
side effects. Prophylactic intravenous administration of ondansetron immediately and 5
minutes preoperatively have shown to provide a protective effect against hypotension while
other studies have shown little effect on the incidence of blood pressure drop in healthy
parturients.
The investigators will study the effect of different doses and timing of intravenous
ondansetron in full term obstetric patients undergoing elective lower segment caesarean
section under spinal anaesthesia on the incidence and severity of hypotension and other
adverse side effects in healthy parturients having the standard intrathecal plain bupivacaine
and fentanyl.