Overview

Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean Section

Status:
Terminated

Trial end date:
2015-12-01

Target enrollment:
0

Participant gender:
Female

Summary

We propose to study the effects on hemodynamics (blood pressure, cardiac output, and central venous pressure) of two doses of bupivacaine for spinal anesthesia during cesarean section: a higher dose of 12 mg to a lower dose of 4.5 mg. We will examine recovery times, incidence of hypotension, and compare pain control and maternal satisfaction during and after cesarean section. We hypothesize that low dose bupivacaine spinal anesthesia will provide equivalent anesthesia for cesarean section compared to conventional dose bupivacaine, with less hypotension, faster recovery time, and enhanced maternal satisfaction. Maternal satisfaction will be assessed by self-reported pain scores, incidence of nausea and vomiting, shivering, and ability to interact with baby in the OR.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

University of Manitoba

Treatments:

Anesthetics
Bupivacaine
Fentanyl
Morphine

Criteria

Inclusion Criteria:

- Adult females having elective, repeat cesarean sections who have given informed
consent.

Exclusion Criteria:

- • Contraindications to dural puncture

- BMI >40

- Elective C/S presenting in labour or with rupture of membranes

- Placenta previa or accrete