Helicobacter Rescue Therapy With Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy
Status:
Recruiting
Trial end date:
2024-06-06
Target enrollment:
Participant gender:
Summary
This study aims at evaluating efficacy and safety of Vonorazon and amoxicillin dual therapy
versus bismuth-containing quadruple Therapy(bismuth#esomeprazole#tetracycline and
furazolidone) in H. pylori rescue therapy. It is hypothesized that Vonorazon and amoxicillin
dual therapy is non-inferior to bismuth-containing quadruple Therapy. Patients with confirmed
failure of H. pylori eradication will be randomized to one of the treatments described above.
At week 6 follow-up visits, a urea breath test#rapid urease test or helicobacter pylori stool
antigen test will be performed to confirm eradication.