Our previous study included 119 Helicobacter pylori(H. pylori)-infected Chinese patients
without previous eradication history who were randomized to low-or high-dose
amoxicillin-vonoprazan regimens consisting of amoxicillin 1 gram either b.i.d. or t.i.d plus
vonoprazan 20 mg b.i.d for 7 or 10 days. Neither 7-or 10-day VA dual therapy with either
b.i.d. or t.i.d. amoxicillin achieved satisfied efficacy (i.e., <90%) when given as
first-line treatment for H. pylori infection. This study evaluated the efficacy and safety of
low-and high-dose amoxicillin-vonoprazan dual therapy for 14 days as first-line treatment for
H. pylori in China.
Phase:
Phase 4
Details
Lead Sponsor:
The First Affiliated Hospital of Nanchang University