Overview

Helicobacter Pylori Eradication With Different Bismuth Quadruple Therapies

Status:
Completed
Trial end date:
2020-08-30
Target enrollment:
Participant gender:
Summary
This study aims to compare efficacy and safety of bismuth-containing quadruple therapy(with rabeprazole amoxicillin clarithromycin)of different kinds of bismuth(Bismuth potassium citrate, pectin bismuth capsules, pectin bismuth particles)in H. pylori first-line eradication. It is hypothesized that different bismuth containing quadruple therapies have comparable eradication efficacy and safety. Patients with confirmed H. pylori positive status will be randomized to one of the treatments described above. At week 2and 6 follow-up visits, a urea breath test(UBT) will be performed to confirm eradication.
Phase:
Phase 4
Details
Lead Sponsor:
Xijing Hospital of Digestive Diseases
Treatments:
Amoxicillin
Bismuth
Citric Acid
Clarithromycin
Potassium Citrate
Rabeprazole
Sodium Citrate