Helicobacter Pylori Eradication With Different Bismuth Quadruple Therapies
Status:
Completed
Trial end date:
2020-08-30
Target enrollment:
Participant gender:
Summary
This study aims to compare efficacy and safety of bismuth-containing quadruple therapy(with
rabeprazole amoxicillin clarithromycin)of different kinds of bismuth(Bismuth potassium
citrate, pectin bismuth capsules, pectin bismuth particles)in H. pylori first-line
eradication. It is hypothesized that different bismuth containing quadruple therapies have
comparable eradication efficacy and safety. Patients with confirmed H. pylori positive status
will be randomized to one of the treatments described above. At week 2and 6 follow-up visits,
a urea breath test(UBT) will be performed to confirm eradication.