Overview

Hedgehog Inhibitors for Metastatic Adenocarcinoma of the Pancreas

Status:
Completed
Trial end date:
2018-02-17
Target enrollment:
Participant gender:
Summary
This is an open-label, single arm, multi-center, Phase II trial to evaluate the progression free survival in patients with metastatic adenocarcinoma of the pancreas treated with a hedgehog inhibitor (GDC-0449) in combination with chemotherapy (gemcitabine and nab-Paclitaxel).
Phase:
Phase 2
Details
Lead Sponsor:
Sidney Kimmel Comprehensive Cancer Center
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Collaborators:
Celgene Corporation
Genentech, Inc.
Stand Up To Cancer
Treatments:
Albumin-Bound Paclitaxel
Gemcitabine
Paclitaxel
Pancrelipase