Heart Rate Controller in Computed Tomography Coronary Angiography
Status:
Recruiting
Trial end date:
2022-03-30
Target enrollment:
Participant gender:
Summary
Coronary computed tomography angiography (CCTA) is one of important non-invasive test for
diagnosis of coronary artery disease. Cardiac motion artifact by heart rate (HR) has impact
on CCTA interpretation. Current recommendation suggests HR reduction at less than 60 bpm with
using of oral metoprolol. However, there are populations that are contraindicated for beta
blockers. There were scantly data of calcium channel blocker and ivabradine. Moreover, there
is no data comparing these 3 drug groups within single trial This double-blinded randomized
controlled trial compares oral metoprolol immediate release, diltiazem immediate release and
ivabradine with primary endpoint of patients' percentage to achieve target HR lower than 60
bpm prior to CCTA.