Heart Failure With Normal Ejection Fraction (HFNEF) in Hemodialysed Patients: Beneficial Effect of Ivabradine

• Status: Completed
• Trial end date: 2012-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Heart failure with normal ejection fraction is often under diagnosed and certainly under treated in hemodialyzed patients. Because of the benefit of reducing heart rate, ivabradine, a pure heart-rate lowering agent without effects on blood pressure, is of potential therapeutic utility.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Second University of Naples; University of Campania "Luigi Vanvitelli"

Criteria

Inclusion Criteria:

• hemodialyzed patients

• signs and symptoms of heart failure with normal ejection fraction

• sinus rhythm

Exclusion Criteria:

• atrial fibrillation/atrial flutter

• valvular heart disease

• unstable angina

• hospitalization for heart failure prior 3 months