Head-to-head Comparison of Diagnosis Value of Keloid on 68Ga- FAPI-04 and 68Ga-RGD PET-CT
Status:
Recruiting
Trial end date:
2024-03-01
Target enrollment:
Participant gender:
Summary
Keloid scars are common benign fibroproliferative reticular dermal lesions. Fibroblasts are
considered to be the key cellular mediators of fibrogenesis in keloid scars. The αvβ3
integrin is a key mediator of angiogenesis and thus may be an important diagnostic and
therapeutic target associated with active keloid development processes. Thus this prospective
study is going to investigate whether 68Ga-FAPI PET/CT and/or 68Ga-RGD PET/CT may provide
evidence for diagnosis and evaluate the effectiveness of treatment.