Half-normal Saline in Idiopathic Left Ventricular Outflow Tract Arrhythmias Ablation

• Status: Unknown status
• Trial end date: 2020-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The study evaluates the use of half-normal saline as an irrigant for open-irrigated catheters during left ventricular outflow tract ventricular arrhythmias ablation. By increasing the efficacy of radiofrequency energy-mediated lesion formation, half-normal saline has the potential to reduce procedural times and improved acute and long-term outcomes.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Texas Cardiac Arrhythmia Research Foundation

Criteria

Inclusion criteria

• male or female between 18 and 75 years of age at the time of enrollment

• undergoing first-time radiofrequency ablation for left ventricular outflow tract ventricular arrhythmias

• written informed consent obtained from subject or subject's legal representative and ability for subject to comply with the requirements of the study

Exclusion criteria

• ventricular arrhythmias originating from the right ventricular outflow tract according to the ventricular arrhythmia ECG morphology (i.e., precordial R wave transition at V3 or later)

• ventricular arrhythmias not originating from cardiac outflow tracts

• baseline hyponatremia (serum sodium level < 135 mEq/L)

• pregnant, breastfeeding, or unwilling to practice birth control during participation in the study

• presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data