Haemodynamic and Cardiovascular Effects of Carbetocin and Oxytocin
Status:
Completed
Trial end date:
2014-01-01
Target enrollment:
Participant gender:
Summary
A double-blinded randomised control trial conducted in the Department of Obstetrics and
Gynaecology of a tertiary hospital, Universiti Kebangsaan Malaysia Medical Centre (UKMMC) for
two years duration from January 1st, 2012 till December 31st, 2013.
The aim of the study is to compare the haemodynamic and cardiovascular effects between
intravenous carbetocin 100 μg and intravenous oxytocin 5 IU in women undergoing elective
Lower Segment Caesarean Section (EL LSCS).
Study hypothesis: A single injection of carbetocin is haemodynamically and cardiovascularly
safe and has similar efficacy in comparison to a single injection of oxytocin.