Overview HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM Status: Recruiting Trial end date: 2025-12-30 Target enrollment: Participant gender: Summary Study to assess the safety and efficacy of HSV-tk (gene therapy), valacyclovir, radiotherapy and chemotherapy in recurrent glioblastoma multiforme. Phase: Phase 1/Phase 2 Details Lead Sponsor: David Baskin MDCollaborator: Center for Cell and Gene Therapy, Baylor College of MedicineTreatments: AcyclovirValacyclovir