Overview

HR+/HER2- Advanced Breast Cancer and Endocrine Resistance

Status:
Recruiting
Trial end date:
2021-10-31
Target enrollment:
Participant gender:
Summary
This is a randomized, 2-arm, open-label, multicenter, international phase II trial. A total of 196 patients will be included. The study will include patients with metastatic Hormone Receptor positive / Human Epidermal Growth Factor Receptor (HER2) negative breast cancer with progressive disease after endocrine treatment. Patients will be randomized (1:1) between two treatment arms: A. palbociclib + fulvestrant and b. capecitabine.
Phase:
Phase 2
Details
Lead Sponsor:
Theodoros Foukakis
Treatments:
Capecitabine
Estradiol
Fulvestrant
Palbociclib