HMPL-004 Maintenance Treatment in Subjects With Mild to Moderate Ulcerative Colitis
Status:
Terminated
Trial end date:
2014-10-01
Target enrollment:
Participant gender:
Summary
A study with an 8 week open label phase study followed by a year long placebo controlled
maintenance phase in subjects with active mild to moderate ulcerative colitis (UC), with a
modified Mayo Score 4-10 and an endoscopy subscore of 2-3, taking mesalamine (or equivalent)
as a concomitant medication. Subjects are required to be in clinical remission or clinical
response to enter the year long maintenance phase. This study will help evaluate if HMPL-004
is effective in subjects maintaining clinical remission following successful induction
therapy achieving clinical remission or clinical response.