HIV-1 Viral Dynamics in Subjects Initiating Raltegravir Therapy in Spain

• Status: Completed
• Trial end date: 2009-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The study purpose is to investigate plasma HIV-1 RNA dynamics in subjects initiating raltegravir-based salvage therapy and quantify the corresponding changes in levels of cellular HIV-1 DNA.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Germans Trias i Pujol Hospital
• Collaborator: Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
• Treatments: Anti-Retroviral Agents; Raltegravir Potassium

Criteria

Inclusion Criteria:

• Patients who have limited or no treatment options due to extensive antiretroviral drug resistance or drug intolerance.

• Subjects initiating raltegravir plus another fully active antiretroviral drug.

Exclusion Criteria:

• Pregnancy, or fertile women willing to be pregnant.

• Active substance abuse or major psychiatric disease.