Overview

HIPEC + FLOT vs. FLOT Alone in Patients With Gastric Cancer and GEJ (PREVENT)

Status:
Recruiting
Trial end date:
2027-05-01
Target enrollment:
Participant gender:
Summary
This is a multicenter, randomized, controlled, open-label study evaluating efficacy and safety of perioperative FLOT chemotherapy plus intraoperative HIPEC versus FLOT chemotherapy alone in patients with resectable localized and locally advanced diffuse and mixed type adenocarcinoma of the stomach and Type II/III GEJ.
Phase:
Phase 3
Details
Lead Sponsor:
Krankenhaus Nordwest
Collaborator:
Deutsche Krebshilfe e.V., Bonn (Germany)
Treatments:
Docetaxel
Fluorouracil
Leucovorin
Oxaliplatin