Overview

HCV Treatment With Fluvastatin, Simvastatin to Improve Interferon Sensitivity

Status:
Terminated
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
Objective: The goal is to improve peginterferon sensitivity in previous poor responders. "Sensitivity" here means the host's ability to kill more HCV. Design: Twenty poor responders to prior PIFN/RBV will be given 48 weeks of statin monotherapy. Veterans and civilians between the ages of 18 and 70 are eligible.
Phase:
Phase 1
Details
Lead Sponsor:
Bader, Ted, M.D.
Treatments:
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Interferons
Peginterferon alfa-2b