Growth Hormone to Increase Immune Function in People With HIV
Status:
Completed
Trial end date:
2007-09-01
Target enrollment:
Participant gender:
Summary
Growth hormone plays an important role in the development of the immune system. Studies
suggest that growth hormone may promote growth of the thymus, a gland responsible for the
production of important immune cells called T cells. Since these cells are lost during the
course of HIV infection, it is possible that growth hormone treatment could help restore the
immune system. This study will determine whether the administration of growth hormone can
increase the size and function of the thymus and cause an increase in the number of new T
cells in the blood of people infected with HIV.
Study hypothesis: Growth hormone treatment will enhance T cell production in HIV infected
adults.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborators:
EMD Serono National Center for Research Resources (NCRR) The J. David Gladstone Institutes University of California, San Francisco