Growth Hormone for Poor Responders in in Vitro Fertilization (IVF)

• Status: Completed
• Trial end date: 2015-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine if growth hormone given 4 weeks before as well as during a cycle of in vitro fertilization will improve outcomes in women who have had previous failure with IVF treatment cycles using high doses of follicle stimulating medications and had a poor response (less than 6 follicles).

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ottawa Fertility Centre
• Collaborator: EMD Serono
• Treatments: Chorionic Gonadotropin; Follicle Stimulating Hormone; Hormones

Criteria

Inclusion Criteria:

• less than 42 years of age

• previous IVF cycle with high doses of gonadotropins (defined as greater than or equal to 400 IU/day)

• produced less than 6 follicles greater than or equal to 15mm

Exclusion Criteria:

• any known contraindications to the approved fertility drugs as per the Canadian Product Monographs

• any contraindications to growth hormone, pregnancy (to be ruled out and documented before GH treatment), or are at risk for gestational diabetes