Growth Hormone Treatment in Children With Hypophosphatemic Rickets

• Status: Completed
• Trial end date: 2011-01-01
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates the effect on height of a two year treatment with growth hormone in 19 children with X linked hypophosphatemic rickets.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bicetre Hospital
• Treatments: Hormones

Criteria

Inclusion Criteria:

• clinical, biochemical and genetic diagnosis of XLH

• height SDS < 2

• at least two years of treatment with oral phosphate and calcitriol

Exclusion Criteria:

• uncontrolled rickets (ALP>600 IU)

• growth hormone deficiency

• hyperparathyroidism, nephrocalcinosis, renal insufficiency

• associated disease

• previous treatment with growth hormone