Granulocyte Colony Stimulating Factor(G-CSF) Therapy for Patients With ACLF
Status:
Unknown status
Trial end date:
2010-08-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to determine whether Granulocyte Colony Stimulating factor(G-CSF)
therapy is effective in the treatment of patients with Acute on chronic liver failure(ACLF).
The investigators hypothesize that ACLF is a disease where severe hepatic impairment is
accompanied by impaired hepatic regeneration. BMC mobilization using G-CSF therapy, or G-CSF
therapy per se would increase the regenerative capacity of the liver and shall lead to
clinical, biochemical and histological improvements in patients with ACLF.