Granisetron in Diabetic Parturients Decrease Spinal Induced Hypotension

• Status: Unknown status
• Trial end date: 2018-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

Diabetic Parturients are exposed to intraoperative hypotension after spinal anesthesia and we proposed that intravenous Granisterone 1 mg will attenuate the hypotension occurred with spinal block during Cesarean sections.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Suez Canal University
• Treatments: Granisetron

Criteria

Inclusion Criteria:

• Type I diabetic patients

• Parturients presented for Cesarean section

Exclusion Criteria:

• Contraindications for spinal anesthesia (like bleeding diathesis or regional infection at site of neuroaxial block)

• Known allergy to Granisetron or local anaesthetic (heavy bupivacaine, Marcaine Spinal 0.5% Heavy, 5mg/ml, AstraZeneca ampule)

• Pregnancy induced hypertension

• Congenital or rheumatic heart diseases

• Antepartum haemorrhage

• Fetal destress or gestational age < 36 week