Gonadotropin-releasing Hormone (GnRH) Downregulation Versus Oral Anticonception Prior to ART in Postoperative Endometriosis Patients

• Status: Unknown status
• Trial end date: 2018-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Does prolonged GnRH downregulation prior to ART improve the clinical pregnancy rate in postoperative endometriosis patients? (A single centre randomised controlled trial)

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universitaire Ziekenhuizen Leuven
• Treatments: Dienogest; Ethinyl Estradiol; Hormones; Triptorelin Pamoate

Criteria

Inclusion Criteria:

• histologically proven endometriosis with complete treatment of all endometriosis lesions during laparoscopy

• only first three ART cycles

• normal uterine cavity

• Eligible for ovarian stimulation with long agonist protocol

Exclusion Criteria:

• FSH>20 IU/L

• presence of large intramural fibroids (> 3 cm)

• <4 oocytes obtained in any previous fresh ART cycle

• ART with sperm derived from testicular biopsy

• ART with Preimplantation Genetic Diagnosis/Screening