GnRH-a and Pregnancy Rate in In Vitro Fertilization (IVF) Cycles.
Status:
Completed
Trial end date:
2010-09-01
Target enrollment:
Participant gender:
Summary
The investigators attempted to establish a rationale for the Gonadotropin Releasing
Hormone-agonist (GnRH-a) administration, post-laparoscopically, in women with mild
endometriosis (until stage II, according to AFS) who underwent IVF-ET procedure. Since GnRH-a
reduces cytokine's concentration in serum (Iwabe et al., 1998; Iwabe et al., 2003) and
peritoneal fluid of women with endometriosis (Taketani et al., 1992) the investigators
hypothesized that GnRH-a can reduces also cytokine's concentration in the follicular fluid
and this action may improve the oocyte quality and the fertility of these women.