GnRH-a and Pregnancy Rate in In Vitro Fertilization (IVF) Cycles.

• Status: Completed
• Trial end date: 2010-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

The investigators attempted to establish a rationale for the Gonadotropin Releasing Hormone-agonist (GnRH-a) administration, post-laparoscopically, in women with mild endometriosis (until stage II, according to AFS) who underwent IVF-ET procedure. Since GnRH-a reduces cytokine's concentration in serum (Iwabe et al., 1998; Iwabe et al., 2003) and peritoneal fluid of women with endometriosis (Taketani et al., 1992) the investigators hypothesized that GnRH-a can reduces also cytokine's concentration in the follicular fluid and this action may improve the oocyte quality and the fertility of these women.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Ioannina
• Collaborators: Tottori University Hospital; University of Patras
• Treatments: Leuprolide

Criteria

Inclusion Criteria:

• Infertility

• Mild endometriosis (until stage II)

Exclusion Criteria:

• ovarian endometrioma > 2 cm

• FSH > 12 mIU/ml

• Mail factor infertility