Glyburide is a medication that has been safely used for several decades to treat non-insulin
dependent diabetes. This pilot study seeks to evaluate whether glyburide, administered at the
lowest dose (1.5 mg/dL daily) to healthy (non-diabetic) subjects is safe both physically and
cognitively. The investigators are hopeful that the results of this study will provide the
necessary foundation to evaluate this medication's use on a larger scale to determine the
feasibility of using glyburide in soldiers either prophylactically or for the treatment of
brain injury.
Phase:
Phase 1
Details
Lead Sponsor:
Washington University School of Medicine
Collaborators:
United States Department of Defense University of Maryland University of Maryland, College Park