Glutamine Effects in Burn Patients

• Status: Active, not recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The study is designed to evaluate the effect of parenteral glutamine supplementation on infection in burn patients.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Menoufia University

Criteria

Inclusion Criteria:

• Age between 18-50 years.

• Total burn surface area of 20% - 60%.

• Expected length of stay in ICU > 48 hr.

• Admission within 72 hrs of burn injury.

• Any thermal injury such as flame burns. Scald burns and contact burns.

Exclusion Criteria:

• Burn patients with hepatic failure.

• Burn patient with Severe renal failure (glomerular filtration rate (eGFR <50 ml/min).

• Patients with inborn errors of amino-acid metabolism (e.g., phenylketonuria).

• Burn patients with pre-existing severe cardiac, pulmonary diseases.

• Burn patients with diabetes mellitus or cancer.

• Patients with metabolic acidosis (pH<7.35).

• Electric burns.