Glucose Regulation During Risperidone and Olanzapine Treatment
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The overall purpose of this research is to look at how two of the most commonly prescribed
newer antipsychotic medications, risperidone and olanzapine, affect substances in the body
such as glucose and insulin. Undesirable changes in blood sugar control, or glucose
regulation, and type 2 diabetes can occur more commonly in individuals with schizophrenia
compared to healthy subjects and subjects with other psychiatric conditions. While
abnormalities in glucose regulation were first reported in schizophrenia before the
introduction of antipsychotic medications, antipsychotic treatment may contribute
significantly to abnormalities in glucose regulation. Attention to the way that antipsychotic
medications may affect glucose regulation has increased as doctors have become more concerned
in general about disease- and drug-related medical complications, including weight gain
during antipsychotic treatment.
Phase:
N/A
Details
Lead Sponsor:
National Center for Research Resources (NCRR)
Collaborators:
Janssen, LP Washington University School of Medicine