Glucocorticoid Induced Whole Body Catabolisme

• Status: Completed
• Trial end date: 2014-06-01
• Target enrollment: 0
• Participant gender: Male

Summary

The main purpose of the trial is to advance our knowledge on the possible mechanism underlying the catabolic effects of long-term treatment with glucocorticoid.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Aarhus
• Collaborator: The Ministry of Science, Technology and Innovation, Denmark
• Treatments: Calcium; Glucocorticoids; Methylprednisolone; Methylprednisolone acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• signed and dated informed consent

• healthy subjects

• sex: male

• age 20-30 years

• BMI 19-26 kg/m2

• normal HbA1c

Exclusion Criteria:

• suspected og known allergy to the trial drug or similar medications.

• known current illness including diabetes mellitus, ischemic heart disease or cardiac arrhythmia.

• Daily drug intake (excluding Over-the-Counter medicines).

• Known or previous mental illness

• Current participation or previous participation in experiments using ionizing radiation for a year prior to inclusion in this study.

• Participation in a larger X-ray examinations in trial period.