Glucagon-like Peptide-2 Mediated Secretion of Stored Enteral Lipids
Status:
Active, not recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
Some of the fat (triglyceride) from the food humans eat gets stored in the bowel. This
triglyceride can then be released into the blood when another meal is consumed or in response
to hormones. How the gut hormone glucagon-like peptide-2 (GLP-2) releases the triglyceride
from the gut is not known. The research team in this study is interested in finding out how
teduglutide (a degradation resistant form of GLP-2) releases stored triglyceride from the gut
by studying samples from patients undergoing endoscopy and small bowel biopsy.