Glucagon Like Peptide 1 Receptor (GLP1R) Expression and Beta-cell Mass in Patients With Type 2 Diabetes

• Status: Recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Validation of the exendin-based beta cell imaging technique in patients with type 2 diabetes

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Radboud University
• Collaborator: University of Coimbra
• Treatments: Exenatide

Criteria

Inclusion Criteria:

• Scheduled for partial or complete pancreatectomy at Radboudumc

Exclusion Criteria:

• Previous treatment with synthetic exendin or dipeptidyl-peptidase IV inhibitors within the past 3 months

• Breast feeding

• Pregnancy or the wist to become pregnant within 6 months

• Creatinine clearance below 40ml/min

• Liver disease defined as aspartate aminotransferase of alanine aminotransferase level of more than three times the upper limit of normal range