Genotypic and Phenotypic Correlates of Resistance to Aspirin

• Status: Completed
• Trial end date: 2011-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The study seeks to identify genomic markers associated with aspirin resistance.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: George Washington University
• Treatments: Aspirin

Criteria

Inclusion Criteria:

• Volunteers 40 to 80 years old willing to sign consent and take 81 mg of aspirin for 7
• 10 days and return for laboratory testing.

Exclusion Criteria:

• Patient requiring more than 81 mg aspirin daily

• Known GI bleeding attributed to ASA

• Active peptic ulcer disease or history within the last year

• Known aspirin allergy

• Current use of:

• warfarin,

• heparin,

• NSAIDs (except aspirin),

• clopidogrel,

• dipyridamole,

• fish-oil/omega 3 supplements,

• Women of childbearing potential who are pregnant, planning to become pregnant or nursing.