Overview

Genicular Nerve Block for Total Knee Arthroplasty

Status:
Completed
Trial end date:
2019-10-22
Target enrollment:
0
Participant gender:
All
Summary
This study seeks to examine the analgesic efficacy of genicular nerve blocks for pain after total knee replacement.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Duke University
Treatments:
Anesthetics
Anesthetics, Local
Bupivacaine
Criteria
Inclusion Criteria:

- Subjects scheduled for primary elective total knee arthroplasty

- American Society of Anesthesiologists Physical Status I-III

- BMI 18-40 kg/m2

Exclusion Criteria:

- Inability to cooperate with protocol

- Inability to understand or speak English

- Allergy to ropivacaine, bupivacaine or other local anesthetic

- Contraindication to peripheral nerve block (e.g. local infection, neurologic deficit
or disorder, previous trauma or surgery to ipsilateral knee, etc.)

- Revision knee surgery

- Chronic opioid consumption (daily morphine equivalent of >30 mg for at least four
weeks prior to surgery)

- History of chronic pain

- History of psychiatric disorder

- History of diabetes mellitus