Overview

Gene Therapy for Chronic Granulomatous Disease

Status:
Unknown status
Trial end date:
2008-12-01
Target enrollment:
Participant gender:
Summary
The aim of the study is to evaluate the side effects and risks after infusion of retroviral gene corrected autologous CD34+ cells of the peripheral blood of chemotherapy conditioned (busulphan)patients with chronic granulomatous disease (CGD). Also gene corrected and functional active granulocytes in the peripheral blood and the engraftment in the bone marrow of the patients will be monitored an documented.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Johann Wolfgang Goethe University Hospital
Collaborator:
German Federal Ministry of Education and Research