Gene Expression Profile of Breast Cancer Samples After Vitamin D Supplementation

• Status: Unknown status
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to evaluate whether calcitriol supplementation may reduce tumor cell proliferation and influence gene expression profile of breast cancer samples from post-menopausal patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Sao Paulo General Hospital
• Collaborator: Instituto Brasileiro de Controle do Cancer
• Treatments: Calcitriol; Vitamin D

Criteria

Inclusion Criteria:

• Postmenopausal women

• Invasive breast carcinoma

• Clinical conditions for breast surgery

• No previous neoadjuvant treatment for breast cancer

• Agreement to take part in the study and sign the informed consent

Exclusion Criteria:

• History of hypercalcemia or nephrolithiasis

• Current use of corticosteroids, vitamin D supplementation, HRT

• Previous chemotherapy, hormonotherapy or radiotherapy

• Parathyroid disease

• Absence of clinical condition to receive supplementation