Gender and Opioid Consumption

• Status: Unknown status
• Trial end date: 2017-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Opioids are widely used for pain relief after major abdominal surgeries[1]. Sex differences in the opioid analgesia have been reported and investigated in human subjects and animal models In this study, effects of sex difference on response to opioid analgesics after abdominal surgeries will be assessed regarding; analgesic duration (primary variable), frequency of analgesic requirement, total opioid consumption, Opioid related complications (respiratory depression, Nausea & vomiting, itching, over-sedation, delayed intestinal motility).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: Morphine

Criteria

Inclusion Criteria:

• ASA I and II Cases scheduled for elective intraabdominal surgeries

Exclusion Criteria:

• diabetes,

• postmenopausal females,

• laparoscopic surgery,

• regional anesthesia emergency procedures,

• sepsis,

• hepatectomy,

• Renal impairment, and

• hepatic impairment,

• mental and psychiatric disorders.