Marginal zone lymphoma, one of the indolent lymphoma, is believed to be incurable with
chemotherapy. Thus the investigators need a novel agent for marginal zone lymphoma.
Gemcitabine has been tried as one of salvage chemotherapy regimen and has been shown to have
anti-lymphoma activity. To the investigators' knowledge, there has been no trial of
gemcitabine for marginal zone lymphoma. Thus the investigators made a plan to investigate the
role of gemcitabine in marginal zone lymphoma.