Gemcitabine and Pemetrexed Disodium in Treating Patients With Advanced Mycosis Fungoides or Sézary Syndrome
Status:
Terminated
Trial end date:
2013-06-04
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop
the growth of cancer cells, either by killing the cells or by stopping them from dividing.
Pemetrexed disodium may stop the growth of cancer cells by blocking some of the enzymes
needed for cell growth. Giving gemcitabine together with pemetrexed disodium may kill more
cancer cells.
PURPOSE: This was planned as a phase I/II trial studying the side effects and determining the
best dose of gemcitabine hydrochloride when given together with pemetrexed disodium.
Unfortunately, due to a lack of funding, the phase II portion was never conducted.
Phase:
Phase 1
Details
Lead Sponsor:
Northwestern University
Collaborators:
Eli Lilly and Company National Cancer Institute (NCI)