Overview

Gemcitabine, Infusional 5 Fluorouracil and Bevacizumab in Patients With Advanced Pancreas Cancer

Status:
Completed
Trial end date:
2011-02-01
Target enrollment:
Participant gender:
Summary
This is a phase II study of biweekly (every other week) bevacizumab followed by gemcitabine then infusional 5-fluorouracil in patients with stage III or IV pancreatic cancer. Patients' response will be evaluated every 8 weeks using usual CT scanning techniques. RECIST (Response Evaluation Criteria in Solid tumors) criteria will be applied to evaluate response. Tumor marker levels (Ca 19-9) will be assessed every 4 weeks, but will not be used to measure response.
Phase:
Phase 2
Details
Lead Sponsor:
Tony Bekaii-Saab
Collaborator:
Genentech, Inc.
Treatments:
Bevacizumab
Fluorouracil
Gemcitabine
Pancrelipase