Gastrointestinal Safety Evaluation of Two Over the Counter Analgesics
Status:
Completed
Trial end date:
2012-07-01
Target enrollment:
Participant gender:
Summary
This study evaluated the effect of oral fast-dissolving formulations of paracetamol and
ibuprofen on the lining of the stomach and duodenum (gastrointestinal mucosa). Endoscopic
examinations were conducted to determine the gastrointestinal damage produced post a 7 day
treatment regimen.